Genetic mutation linked to schizophrenia in both humans and mice
A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers at the University of Illinois Urbana-Champaign and colleagues in Massachusetts and Germany.
Mice With a Human Gene Started Squeaking Differently. Could This Tiny Genetic Mutation Explain the Origin of Speech?
In a lab at Rockefeller University in New York, a mouse squeaks. But this is no ordinary squeak. It is a strange, complex sound, unlike anything heard from a mouse before. The difference lies in a single gene — a gene that may hold the key to one of humanity’s most defining traits: the ability to speak.
A human gene makes mice squeak differently — did it contribute to language?
A gene variant present in most people might have contributed to cognitive differences between humans and their closest relatives.
Mice With a Human Gene Mutation Start ‘Talking’ Differently—And It Might Be Why We Speak
A new study has revealed that a single genetic mutation, found in all modern humans but absent in Neanderthals and Denisovans, could have played a role in the evolution of speech and language. The research,
Scientists Put a Human Language Gene Into Mice And Changed Their Voice
A new contender for a human 'language gene' can change the way that mice squeak when it is incorporated into their DNA. The gene is called NOVA1, and in our own species, it is remarkably unique. While virtually all other mammals have the same NOVA1 variant in their genetic code,
Mutation increases enzyme in mouse brains linked to schizophrenia behaviors
A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with ...
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Epigenetic modifiers: catalytic or noncatalytic, that is the question
Both Setd2-CD and Setd2-KO mice exhibited embryonic lethality ... the generation of point mutation CD knockin animal models and direct comparison with KO models is considered an objective ...
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Lithium as a Promising Therapeutic Option for Treating Autism Spectrum Disorder
Subscribe for FREE Among the many genetic risk factors for ASD, Dyrk1a mutations stand out as significant ... and behavioral phenotypes in DYRK1A-knockin mice. Mol Psychiatry. 2024. doi: 10.1038 ...