OPTYX study shows many patients with advanced prostate cancer preferred oral relugolix over injectables for androgen deprivation therapy.

Androgen suppression with abiraterone acetate, leuprolide, PARP inhibition, and stereotactic body radiotherapy (ASCLEPIuS) in high-risk and node positive prostate cancer (PCa): Phase I multicenter ...

agonists like leuprolide acetate or goserelin acetate. Myfembree combines relugolix – a small molecule, GnRH receptor antagonist – with two hormonal drugs (oestradiol and norethindrone acetate ...

Hypertension was the most common grade ≥3 adverse event, observed most frequently in the ADT + apalutamide + abiraterone acetate/prednisone arm (19% ... patients in the combination arm of enzalutamide ...

9 The only published trial of combination MDT with androgen receptor pathway inhibitors in oligorecurrent metastatic prostate cancer patients is the phase II SATURN trial, in which patients received ...

Exposure to ADT included gonadotropin-releasing hormone (GnRH) agonists (leuprolide, buserelin, goserelin, triptorelin), oral antiandrogens (cyproterone acetate, flutamide, bicalutamide, nilutamide), ...

I f prostate cancer has spread to other areas of your body, your doctor may recommend androgen deprivation therapy (ADT), which halts the production of androgen hormones, especially testosterone ...

Prostate Health is important for men. More than 30 million men suffer from prostate conditions that negatively affect their quality of life. The prostate enlarges in size as a man grows old and ...

The majority of women with uterine fibroids are asymptomatic, consequently get less clinical attention and fibroid tumors often remain undiagnosed. [23,24] Symptomatic women typically complain ...

This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...

Sex hormones have been implicated in neurite outgrowth, synaptogenesis, dendritic branching, myelination and other important mechanisms of neural plasticity. Here we review the evidence from animal ...