The discovery and development of GLP-1 receptor agonists for type 2 diabetes and obesity is a bench-to-bedside success story.1 Multiple GLP-1 receptor agonists are now in clinical use, such as ...

A recent Brazilian study published in Nature Cardiovascular Research has highlighted promising pathways for preventing and treating atrial fibrillation, a condition that significantly raises the risks ...

The study carried out by Dr Marta Moreno-Rodríguez in the UPV/EHU group showed that the neurotransmitter receptors in the ... study of this new therapeutic pathway. To this end, they are working ...

The pathogenesis of some kidney diseases is closely associated with complement activation, where the C3a/C3a receptor (C3aR ... with disease progression and severity. The C3a/C3aR pathway facilitates ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Hope is not passive wishing but an active, dynamic process. According to Hope Theory, hope involves two components: agency and pathways. Agency is the belief in one’s capability to act ...

MANILA, Philippines — A bill to allow graduating junior high school students to pick alternative education pathways has been approved on third and final reading by the House of Representatives ...

This discrepancy indicates that the etching procedure introduced extraneous conductive pathways unrelated to the VHE, thereby explaining why a reduced band gap had been observed in prior ...

A breakthrough study sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and memory.

In addition to NK cell-mediated killing by cytotoxic granules, activated NK cells can induce cell death in target cells through activating the death receptor pathway. Here a protein, known as death ...