One way to improve the traditional egg-based influenza vaccines involves delivering a higher dose of viral antigens (i.e., four-fold higher than the standard vaccine) or incorporating adjuvants (such ...

2016). Different regions of HA, including the globular head, the stalk and the ectodomain (contains the head and stalk), fused with the intramolecular adjuvant IgG Fc were expressed. These vaccines ...

Spirulina has solid potential as a therapeutic adjuvant, according to researchers in Australia who isolated extracellular vesicles (EVs)—nanoscale vesicles enclosed with bilayer phospholipid ...

Apart from the aforementioned signal 1-providing adjuvants, a large number of adjuvants have been investigated that do not directly affect the concentration and distribution of antigen between ...

2009;8(3):293-298. A new generation of vaccine antigens with little or no inherent immunostimulatory properties requires potent adjuvants to enhance and direct the vaccine-induced immune response.

There is a commercial access agreement for durvalumab. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisations can contact ...

There is a commercial access agreement for pembrolizumab. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisations can contact [email protected] ...

The patients were randomly assigned to receive adjuvant treatment with T-DM1 at 3.6 mg/kg (n=743) or trastuzumab at 6 mg/kg (n=743) every 3 weeks for 14 cycles. Baseline characteristics were ...

an MF59-adjuvanted trivalent inactivated subunit vaccine (Fluad ®, Seqirus). All inactivated influenza vaccines (IIV) available in Canada are produced in eggs, except for Flucelvax Quad (IIV4-cc), ...

Understanding the modalities of IL-1 activity during T cell activation thus could hold major implications for rational development of the next generation of vaccine adjuvants. A limitation of the ...