The most comprehensive approach, illustrated in Figure 2A using the example of SSRIs ... potentially impacts numerous serotonin receptor subtypes, spanning multiple signaling processes (pre ...

Mark Bear of the Massachusetts Institute of Technology in Cambridge and his colleagues found that the lack of FMRP leads to dysregulation of signaling through the metabotropic glutamate receptors ...

Many Medicaid enrollees with type 2 diabetes have restricted access to cardioprotective medications, including sodium-glucose ...

Drugs that bind to and activate the receptors for the hormones GLP-1 and GIP are effective in the treatment of obesity and ...

Combined single-molecule spectroscopy, hydrogen–deuterium exchange and molecular dynamics approaches reveal that agonist activation of metabotropic glutamate receptors entails population of ...

A new study explores why some individuals are more inclined to help others, finding key differences in brain activity and ...

The effects that result depend on where the receptor is located and which endocannabinoid it binds to. For example, endocannabinoids might target CB1 receptors in a spinal nerve to relieve pain.

for example, the role played by glutamate and GABA. Current evidence suggests that blood oxygen level-dependant effects of antipsychotic drugs reflect specific, regional effects as opposed to ...

They work by activating the glucagon-like peptide 1 receptor (GLP-1R) to stimulate insulin secretion, which makes one feel fuller for longer. 1 “[The study] just really goes to show that the adipose ...

“I tested this product once a day for 3 days. Almost immediately, I noticed the relaxing effects of the CBD oil. It noticeably reduced the stress I felt and made me feel ready for bed.

The anaphylatoxin C3a mediates pro-inflammatory and chemotactic functions through the G protein-coupled receptor C3aR. While the active structure of the C3a-C3aR-G i complex has been determined, the ...

(A) : Inputs and assumed supralinearity that could solve the NFBP: The NFBP is represented with an example from visual feature binding. In the simplest form of the NFBP, a stimulus has two features, ...