1% of mitochondrial proteins are encoded by the mitochondrial genome and synthesized in the mitochondrial matrix. The translocase of the outer membrane (TOM) complex is the main entry gate used by ...
Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...
A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...
BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.
Mitochondria contain the mitochondrial electron transport chain (ETC), or a series of protein complexes in which electrons pass through and produce ATP, or energy, for the cell. Mitochondrial ETC ...
mtDNA molecules are compacted into mtDNA-protein complexes termed nucleoids. Mitochondrial nucleoid proteins compact and protect mtDNA and impact mtDNA transcription. Mass spectrometry studies ...
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Study finds RNA modification is responsible for disruption of mitochondrial protein synthesis in Alzheimer's diseaseND5 plays an important role in this connection, and any mutations of the mitochondrial ... and fewer proteins of the subunit ND5, which is of central relevance to complex I, are formed because ...
As a result, more energy-producing proteins can be ... cells to compensate for reduced Complex III activity, highlighting the dynamic and flexible nature of mitochondrial structure and function.
The study shows that mitochondria do more than provide energy; they play an active role in modulating the immune response.
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