Diet plays a pivotal role in influencing autoimmune diseases like multiple sclerosis (MS), inflammatory bowel disease, and ...

Immunotherapy treatment was effective at reducing attack recurrence in patients with NMOSD but was less effective for MOGAD, a study found.

Iron accumulation in myelin-producing cells called oligodendrocytes is also a marker of Alzheimer's, as excess iron can result in oxidative stress, affecting myelin—an insulating layer that ...

Patient enrollment has been completed ahead of schedule in a Phase 2 clinical trial evaluating Contineum Therapeutics‘ PIPE-307, an oral therapy aiming to restore myelin — a process known as ...

When comparing ERDs with PRDs, our results showed a higher number of early-stage BCAS1 + oligodendrocytes in PRDs compared to ERDs in remyelinated lesions. However, no significant differences were ...

Shin says the objective of the research is to characterize the inflammation triggered by GALC deficiency in both oligodendrocytes — the cells that produce myelin — and the brain’s immune cells called ...

In other cases, there may be autoantibodies against the myelin oligodendrocyte glycoprotein (MOG) or patients may be double seronegative, i.e., they don’t have antibodies against either AQP4 or MOG.

Shin says that the objective of the research is to characterize the inflammation triggered by GALC deficiency in both oligodendrocytes — the cells that produce myelin — and the brain’s immune cells ...

Previous findings from our group indicated that 1,25-dihydroxyvitamin D3 (1,25-VitD3) has a protective effect when given alone or in combination with the specific autoantigen (myelin oligodendrocyte ...