Ubiquitin-binding domains (UBDs) are modular elements that bind non-covalently to the protein ... DNA damage responses and inflammatory pathways. UBD preferences for distinct ubiquitin chains of ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

(C) Incorporating the IDEA-optimized energy model into the simulation model improves the prediction of protein-DNA binding affinity, compared to the prediction by the previous model with electrostatic ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism—a novel genomically recoded organism ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...

Financial writer recommends Voyager Therapeutics, Inc. for high-risk investors due to promising preclinical Alzheimer's ...

Elicio Therapeutics aims for breakthrough treatment with ELI-002 in pancreatic cancer. Find out why ELTX stock may benefit ...

Together, these findings demonstrate that the EndoIII-dsDNA binding is governed by a balance of enthalpic and entropic contributions, enabling a specific and structured interaction critical for ...