Guselkumab targets the p19 alpha subunit of IL-23. While IL-23 promotes normal inflammatory and immune responses, the p19 and ...
Welcoming a new baby is a major life transition ? one that can be both physically taxing and psychologically taxing. It is normal to feel a range of emotions, from joy and excitement to anxiety to ...
Objective Combination therapy with rituximab and belimumab is a novel treatment strategy for severe SLE and lupus nephritis.
The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...
A fungal infection has been shown to trigger a fruit fly's own immune system to destroy brain cells leading to signs of neurodegeneration, a new study has found.
Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...
This important study explores the conserved role of IgM in both systemic and mucosal antiviral immunity in teleosts, challenging established views on the differential roles of IgT and IgM. The ...
Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.
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During a physical exam, swollen lymph nodes, skin issues, or a spleen that is larger than normal may be noticed. An overall low white blood cell count (leukopenia) is most often detected when your ...