These include famous genes such as K-ras and p53. One notable exception is the cyclin-dependent kinase inhibitor p27 Kip1. p27 is an inhibitor of the cell cycle, and thus a candidate tumor ...

and of reduced expression of p27 KIP are associated with various lymphomas, adenomas, carcinomas and gliomas. These properties of altered cellular cyclins resemble the observed functions of viral ...

(Mayor Junard ‘Ahong’ Chan FB) The massive P27-billion project was sealed through the signing of the memorandum of understanding (MOU) on Thursday, March 6. Leading the signing of the MOU was Metro ...

Icaritin (ICA) is a prenylflavonoid natural product extracted from plants of the Epimedium genus. The approval of ICA softgel capsules as a class 1.2 traditional Chinese medicine (TCM) innovative drug ...

Interestingly, p53 WT interacts with both p130 and p107. This is likely due to the cell cycle-regulated expression of p130 and p107, where p130 is predominantly expressed in the G0/G1 phase and p107 ...

This in turn leads to cell cycle progression through activation of cyclins (D and B), as further confirmed by lower levels of p53 and its downstream genes (p16, p21 and p27) (Yadav et al., 2020).

In recent years, hyperoside (quercetin 3-O-β-D-galactopyranoside) has garnered significant attention due to its diverse biological effects, which include vasoprotective, antioxidant, anti-inflammatory ...