This dramatically improves the uptake of a promising class of cancer-fighting drugs called PROTACs. The new drug design deliveries up to 22 times more of he drug inside cancer cells, and tumor ...

The strategy was particularly successful for a class of complex, large-sized drugs known as bRo5 molecules, such as PROTACs, a type of targeted cancer therapy that breaks down proteins in cells.

Scientists at Duke University School of Medicine, University of Texas Health Science Center at San Antonio, and University of Arkansas have found a way to improve the uptake of a promising class of ...

The strategy was particularly successful for a class of complex, large-sized drugs known as bRo5 molecules, such as PROTACs, a type of targeted cancer therapy that breaks down proteins in cells.

The paper underscores the potential of PROTACs to address unmet needs in crop resilience, productivity, and sustainability — with the precision and adaptability that modern agriculture demands.

Scientists at the Charlie Dunlop School of Biological Sciences at UC Irvine report that they have developed a powerful new tool, called Phollow, that lets scientists watch viral activity in the ...

The paper underscores the potential of PROTACs to address unmet needs in crop resilience, productivity, and sustainability — with the precision and adaptability that modern agriculture demands. This ...

Proteolysis-targeting chimeras (PROTACs) are molecules that are opening up new targets by driving their degradation, but regulators have not yet approved any PROTACs as drugs. Fischer points out ...

No sooner did Eli Lilly (NYSE: LLY)’s oral diabetes candidate orforglipron make history Thursday as the first oral small molecule glucagon-like peptide-1 (GLP-1) receptor agonist to ace a Phase ...