The drug is a recombinant version of the enzyme alpha-glucosidase, which is deficient in Pompe disease, leading to the accumulation of glycogen to toxic levels that damage muscle cells.

Patients with advanced solid tumors experienced significantly improved survival outcomes when receiving a tailored therapy ...

Lean muscle supports mobility, balance and resilience during illness or injury. In contrast, excess visceral fat (around the internal organs) increases the risk of disease. Muscle is made of ...

Apr. 29, 2025 — Daily exposure to certain chemicals used to make plastic household items could be linked to more than 356,000 global deaths from heart disease in 2018 alone, a new analysis of ...

According to the Centers for Disease Control and Prevention ... through the lining of the bladder but have not yet invaded the muscle layer. NMIBC is associated with high rates of recurrence ...

These include proinflammatory cytokines, renal function tests, and cardiac insufficiency markers, which help assess the risk of disease progression. “Standard biomarkers that inform on organ function, ...

AI’s capacity to analyze and classify large volumes of data can be leveraged to enhance both diagnosis and management in Fabry disease. Artificial intelligence (AI)-based tools could improve the ...

The diagnosis was established by reduction of dysferlin in the muscle biopsy and subsequent mutational analysis ... a challenge to understanding the underlying pathomechanisms in this disease. muscle ...

READ MORE: Penn used an AI tool matched a patient’s rare disease with a common drug Each image is 1-20 gigabytes — extremely large and high-resolution files that allow pathologists to zoom in to ...