The researchers focused on the three-protein CST complex and the DNA polymerase α/primase (PP) complex, which are important for the proper upkeep of telomeres. "We found that DNA polymerase α is ...

Attribution (BY): Credit must be given to the creator. The study of “resource allocator” bacteriophage T7 RNA polymerase (T7RNAP) has garnered significant interest, particularly for optimizing ...

Primary cell experiments used 100 nM AZD5582 and 500 nM I-BET151 for 24 hr for qPCR, and then treatment was extended to 72 hr for viral RNA detection in the supernatant. Cells were treated with 10 ...