RNA Polymerase III (Pol III ... specifically those containing the subunits POLR3G and POLR3GL, can significantly influence transcriptional outcomes and cellular behavior in cancerous tissues.

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex ... for both transcription and RNA replication and mutations that have ...

while loss of PRC2.2-specific subunits resulted in sensitivity. Data from CUT&RUN and RNA sequencing experiments performed on clonal MTF2∆ and JARID2∆ knockout mutant cell lines suggest that PRC2.1 ...

Mitochondrial RNA polymerase (POLRMT) is an RNA polymerase that executes the transcription of the mtDNA. In comparison to the POLγA-related neurological diseases, a relatively less neuronal pathology ...

Aging is an inevitable progressive decline in physiological organ function that increases the chance of disease and death. The renin–angiotensin system (RAS) is involved in the regulation of ...

The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead ...

This valuable work examines the role of the oxidoreductase MftG in Mycolicibacerium smegmatis alcohol metabolism. A solid set of data is presented to show that, in the context of ethanol metabolism, ...

Department of Microbiology and Cell Biology, Indian Institute of Science, C.V. Raman Avenue, Bangalore 560012, India ...

Department of Chemistry and Biochemistry, Baylor University, Waco, Texas 76798, United States ...