which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the process of transcription is the complex of ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do. Moreover, each step in the flow of ...

More information: Yuki Aoi et al, SPT5 regulates RNA polymerase II stability via Cullin 3–ARMC5 recognition, Science Advances (2025). DOI: 10.1126/sciadv.adt5885 Provided by Northwestern University ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...