This inhibition results in reduced phosphorylation of extracellular signal-regulated protein kinase (ERK) 1/2 and its downstream target p90 ribosomal S6 kinases (RSK/P90), along with decreased ...
2012). Hence, CEBPD likely raised cell viability and proliferation through the upregulated phosphorylation levels of MAPK3/1, PI3K, AKT1, mTOR, RPS6, and EIF4EBP1 in UC cell lines (38). The mTOR is ...
ABSTRACT Introduction: The treatment of elderly multiple myeloma (MM) patients with autologous stem cell transplantation (ASCT) is a controversial procedure. Most clinical trials evaluating the safety ...
Objective Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with limited treatment options. Cabozantinib, an orally bioavailable multikinase inhibitor is now approved by ...
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