coli replisome. (B) Cartoon of high- and low-fidelity DNA polymerase ... Single-molecule fluorescence imaging in live bacterial cells. (A) Structure of fluorescent proteins derived from Aequorea.

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

This important study presents compelling observational data supporting a role for transcription and polysome accumulation in the separation of newly replicated bacterial chromosomes. The study is ...