RNA polymerases are sloppy. A retrovirus with an RNA genome, which is copied into DNA by a reverse transcriptase, is prone to mutations because the enzyme lacks the 3’ to 5’ proofreading capability of ...

More than 46,000 of them had been prescribed a form of HIV-suppressing medications known as reverse transcriptase (RT) inhibitors. Among this subgroup, Alzheimer's diagnoses occurred in about 2.5 ...

Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) and protease, the molecular targets of anti-retroviral drug therapy, are prime examples of genes in which ...

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) Non-nucleoside reverse transcriptase inhibitors (NNRTIs) prevent HIV from making copies of itself by binding to and stopping the enzyme ...

The four main classes, which most people are treated with, target one of three viral proteins which control HIV’s lifecycle: reverse transcriptase, integrase and protease. Historically, most people ...

The researchers evaluated respiratory specimens for influenza type and subtype via reverse-transcriptase polymerase chain reaction (RT-PCR) and estimated influenza VE by virus type/subtype and by age ...