Unlike ribosomal peptides, which are synthesized using ribosomes ... This research not only clarifies the synthesis process but also opens avenues for re-engineering NRPSs to create new ...

and ribosomes to produce proteins via reactions that differ in details from dehydration synthesis. Some peptides, like alpha-amanitin, are called ribosomal peptides as they are made by ribosomes, but ...

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...

The enzyme Cfr, for instance, alters ribosomal RNA ... provided insights into how the ribosome functions during active protein synthesis, revealing structural details that could inform future ...

Understanding these fundamental processes holds great potential for developing new antibiotics that target these specific pathways in bacterial protein synthesis, according to the researchers.

The rRNA structures also provide binding sites for ribosomal proteins ... which catalyzes the formation of peptide bonds between amino acids during protein synthesis. This discovery led to the concept ...

Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...

Protein synthesis refers to the process by which ... The 30S subunit contains a 16S ribosomal RNA (rRNA) molecule, while the 50S subunit harbors 23S and 5S rRNA molecules. In contrast, eukaryotic ...

Ribosomal translation is the process by which cells synthesize proteins based on the genetic instructions encoded in messenger RNA. It is essential for life, yet it is an incredibly complex process ...

Despite redundant cellular pathways to minimize translational errors, errors in protein synthesis are common. Pathways and mechanisms to minimize errors are classified as pre-ribosomal or ribosomal.