Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...

One study used a ribozyme combined with an AAV vector (rAAV-SynRz). Nigrostriatal injection of rAAV-SynRz in MPP+-treated adult rats, which has increased expression of α-syn (Kühn et al., 2003), ...

Riboswitches are RNA sensors that allow bacteria to sense and respond to their environment. Here, Bushhouse et al. demonstrate that the sensitivity of several riboswitches can be tuned by ...

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

Feb. 4, 2025 — Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the ...

The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead ...