Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides ...

Getting therapeutic drugs past the blood-brain barrier has long been one of medicine's most difficult challenges, limiting ...

Learn more at realid.dmv.ca.gov. The Pleasanton Downtown Association is hosting its annual Bunny Hop Scavenger Hunt for the Easter season next Saturday (April 19) from 10 a.m. to noon. The free event ...

A scavenger was electrocuted at the excavation site of a flood control project of the Department of Public Works and Highways (DPWH) flood control project in Pasay City on April 10. Pasay City Police ...

It’s still the perfect opportunity to keep your children entertained with a variety of activities, from Easter egg hunts to nature-themed scavenger hunts. For example, Dubai-based homemaker ...

Get Instant Summarized Text (Gist) A novel drug compound has been identified that selectively activates delta opioid receptors, offering pain relief without the dangerous side effects associated ...

Mattei expanded on this subject. “The way naloxone works — once you give the person the naloxone, it’s going to interact with that opiate receptor and that person will come out of the high ...

The anaphylatoxin C3a mediates pro-inflammatory and chemotactic functions through the G protein-coupled receptor C3aR. While the active structure of the C3a-C3aR-G i complex has been determined, the ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

The facelifted Volvo XC90 has arrived in Singapore in two forms – the B5, a 2-litre mild hybrid with 250hp; and the T8, a plug-in hybrid that combines a 310hp 2-litre engine with a 145hp ...

This patent highlight describes a series of novel 2-pyrrolidone derivatives that act as negative allosteric modulators (NAMs) of GluN2B-containing N-methyl-d-aspartic acid receptors (NMDARs). These ...