Nocion Therapeutics, Inc., a clinical stage biopharmaceutical company developing novel small molecule charged sodium channel blockers called "nocions", that selectively affect actively firing ...

This seems to be true of all of them. There are also drugs known as calcium channel blockers, such as Amlodipine, Diltiazem, or Verapamil. As a group, they rarely cause erectile dysfunction.

New York, USA, April 09, 2025 (GLOBE NEWSWIRE) -- Sodium Channel Blockers Clinical Trial Pipeline Accelerates as 20+ Pharma Companies Rigorously Developing Drugs for Market Entry | DelveInsight ...

Due to the effect of beta-blockers on nutrient absorption, your doctor may recommend that you decrease your intake of sodium and/or calcium. Also, keep in mind that orange juice may interfere with ...

Nonetheless, it seems noteworthy that other chemically unrelated sodium channel blockers, such as TTX, [46,49,50] and knockdown of sodium channels by use of short hairpin RNA (shRNA), [49] have ...

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Nat Clin Pract Neurol. 2008;4(3):159-169. Despite the fact that phenytoin has been used successfully in the past to treat positive symptoms in patients with MS, the investigators at Yale ...

Oct. 17, 2024 — Researchers describe how -- even more than just the presence of sugar and salt in the diet -- having more ultra-processed foods laden with additives can lead to higher average ...

This was inconsistent with reports from previous studies (61) suggesting the discontinuation of sodium channel blockers as effective therapy against seizures in SCN1A-positive patients. This indicates ...

to evaluate a mechanism by which sodium channel blockers can reduce J-waves. For these purposes we used a computational approach. We also employed a pig model to replicate the computational findings ...