Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease.

In this study, we investigated and compared the expression patterns of the REIC/Dkk-3 protein in mouse squamous epithelia. Expression of REIC/Dkk-3 in the back skin was localized to the upper ...

Enrollment into the two sequential cohorts was not randomized or stratified. Patients were monitored for disease ... New York esophageal squamous cell carcinoma 1. The stage at screening for one ...

Patients with adolescent and young adult (AYA) cancer are recognized as a vulnerable subpopulation in high-income countries (HICs). Although survival gaps between HIC and low- and middle-income ...

This delicate procedure requires technical skill for the preparation of AM with attached corneal epithelial cells and surgical dexterity to manipulate the AM onto the ocular surface. As previously ...

Morphological studies of the cardia in GORD should focus on tissue samples that contain both squamous and columnar epithelium in order to obtain an accurate picture of the spectrum of injury. This ...

This valuable study investigated the role of PLECTIN, a cytoskeletal crosslinker protein, in hepatocellular carcinoma development and progression. Using a liver-specific Plectin knockout mouse model, ...

TNBC cells with centrosome amplification, but not normal breast epithelial cells, depend on OTUD6B to proliferate. Indeed CRISPR-Cas9 editing results in only OTUD6B-/+ TNBC cells which fail to divide ...

In the oesophagus, 14 cell types were identified among 87 947 cells. Over 90% of the cells fell into four major epithelial cell types: upper, stratified, suprabasal and dividing cells of the ...

Background: Oral probiotic dietary supplements are widely used in veterinary medicine, including in horses. It is hypothesized that the presence of probiotic strains can both modulate the intestinal ...