A mutation that helps insects survive our chemical onslaught has been found in one of the worst places imaginable: the genome of the common bed bug.

Patients with gene mutations known as epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 L858R substitution mutations will be eligible for therapy. Additionally, the EC has ...

for the first-line treatment of adult patients with advanced non-small cell lung cancer with epidermal growth factor receptor exon 19 deletions or exon 21 L858R substitution mutations, and as a ...

for the first-line treatment of adult patients with advanced non-small cell lung cancer with epidermal growth factor receptor exon 19 deletions or exon 21 L858R substitution mutations ...

Sustained reactivation of mutant p53 drives durable anti-tumor activity across models, including KRAS co-mutant tumorsFMC-220 selectively stabilizes p53 Y220C at lower doses, overcoming key ...

We have discovered two types of 5′ intronic gene mutation that impair androgen receptor (AR) mRNA expression severely, and cause complete androgen insensitivity. Labium majus skin fibroblasts ...

AVI-4303, which is a C5 benzotriazole analog, exhibited ten-fold higher potency than AVI-3318. Comparatively, N1 propargyl ...

Health and Human Services Secretary Robert F. Kennedy has sparked widespread outrage with disparaging remarks about autism ...

Although the genetic interactions among mutations in starch biosynthesis ... leading to an amino acid substitution which disrupts the enzyme activity, while in hvbe2a-2, HvBE2a was absent due ...

The MET/EGFR-targeted antibody is approved as a first-line therapy for patients with advanced NSCLC with EGFR exon 19 deletions or exon 21 L858R substitution mutations in combination with J&J's ...