Plasma cells (PCs) are the terminal differentiation stage of activated B cells and serve as crucial effector cells in humoral immunity. While PCs have ...

γδ T cells can be divided into different subsets based on the composition of the TCR chains ... Production of IFN-γ, TNF-α and granzyme B was measured using flow cytometry. The target cells WM9, WiDr, ...

Alterations in virtually all intestinal cell types ... A recent study combining scRNA-seq, flow cytometry and high-content imaging (spatial proteomics) delineated the localisation of different stromal ...

To support physicians in treating cancer patients, oncology laboratories can benefit from adopting end-to-end automation of flow cytometry workflows ... variability in cell population frequencies ...

Here, the authors use a double-reporter system to tag IFNγ-producing versus IL-17A-producing γδ T cells to compile a trancriptomic resource of these cell subsets in mice at steady state and in ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...

These include specific genetic and epigenetic changes in the cancer cell and/or the microenvironment in which the cancer cell resides. The proteomic landscape of muscle-invasive bladder cancer ...

1 Day TMUS -0.60% DJIA -0.75% S&P 500 -0.50% Telecommunication Services -0.79% ...

The instability and/or plasticity of immune cells are known to influence their functions, which would further regulate the balance between tolerance and autoimmunity. The plasticity of regulatory T ...