Another kind of RNA therapy that has been approved by regulators in the U.S. and Europe alike, are antisense oligonucleotides. These work by binding to specific mRNA sequences in order to modify gene ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

New research published in the Journal of Chromatography A examines the effect of flow rate on plate height and resolution for antisense oligonucleotides ... ONs are short single- or double-stranded ...