Nature18d
Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5
Seven-transmembrane segment, G protein-coupled receptors play central roles in a wide range of biological processes, but their characterization has been hindered by the difficulty of obtaining ...
Frontiers19d
The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28
The impact of the hinge domain (HD) and the transmembrane domain (TMD) between the extracellular antigen-targeting CARs and the intracellular signaling modalities of CARs has not been systemically ...
C&EN1mon
Free Energy, Rates, and Mechanism of Transmembrane Dimerization in Lipid Bilayers from Dynamically Unbiased Molecular Dynamics Simulations
Here, we present a method to obtain free energy, rates, and mechanisms of transmembrane dimerization from simulations without using biasing forces or needing good predefined CVs. We build on our ...
Frontiers4y
Chemokine-Like Factor-Like MARVEL Transmembrane Domain-Containing Family in Hepatocellular Carcinoma: Latest Advances
Chemokine-like factor (CKLF)–like MARVEL transmembrane domain-containing family (CMTMs) is a new gene family, consisting of CKLF and CMTM1 to CMTM8, which plays an important role in hematopoiesis ...