The San Francisco 49ers got a great performance out of rookie running back Isaac Guerendo in his first career NFL start in Week 14 against the Chicago Bears. However, the fourth-round rookie ...

The San Francisco 49ers have some work to do to get their offense back on track after a rough 2024 season. While getting ...

The San Francisco 49ers 2024 season is officially over after ... the season finale came with one final trick up its sleeve as running back Isaac Guerendo was carted off the field early in the ...

Coach Kyle Shanahan said after Sunday's 47-24 loss to the Cardinals that Guerendo (knee/ankle) likely suffered an MCL sprain and will undergo further testing Monday, Lindsey Pallares of the 49ers ...

Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, Matt Barrows of The Athletic reports. The 49ers' 2024 campaign is over, but the team's season ...

San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated: ACL is good, thank you GOD. I'll be back ...

The 49ers might have to reach a little further down their depth chart to find another starting running back. Rookie running back Isaac Guerendo sustained a foot sprain in the 49ers’ 38-13 ...

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped five of their last six matchups. The 49ers last met Detroit in the NFC ...

San Francisco 49ers Isaac Guerendo was carted off the field Sunday against the Arizona Cardinals. He suffered the injury after a scary tackle during the first series of the game. The 49ers drafted ...

Guerendo also praised the 49ers' locker room culture, noting that he's leaned on advice from teammates on both sides of the ball. He credited linebacker Fred Warner, among others, for their guidance.

One key player who was questionable to suit up this week is Isaac Guerendo, the 49ers running back, but good news was released on Saturday that he is expected to play tonight. He has averaged an ...

San Francisco 49ers running back Isaac Guerendo is dealing with a hamstring injury and is unlikely to play Sunday at the Miami Dolphins, a source told ESPN's Adam Schefter on Thursday. Guerendo ...