A year ago, the 49ers beat the Lions in the NFC Championship at Levi's Stadium. What a difference a year makes. On Thursday, ...

The 49ers will have their best pass rusher today. Defensive end Nick Bosa officially is active for the 49ers' Week 16 game ...

The San Francisco 49ers face unexpected challenges this season, with a 6-9 record and playoff hopes dashed. Defensive star ...

The 49ers had a couple of key defensive players listed as questionable for Sunday's game in Miami and both of them got the ...

Ruled out Friday were left tackle Trent Williams (for the fifth straight game) and running back Isaac Guerendo (hamstring, ...

Kyle Shanahan called running back Isaac Guerendo a long shot to play against the Dolphins earlier this week and he moved to ...

After Sunday's game at Hard Rock Stadium, San Francisco 49ers defensive end Nick Bosa and Miami Dolphins head coach Mike ...

San Francisco 49ers linebacker Dre Greenlaw and defensive lineman Nick Bosa are active for the team's Week 16 matchup vs. the ...

Bosa logged a LP/DNP/LP practice week while working through hip and oblique injuries, but the veteran pass rusher has done enough to be cleared for Sunday's game. He registered four tackles (two solo) ...

The San Francisco 49ers released their latest injury updates headed into the team's Week 16 matchup vs. the Miami Dolphins.

The San Francisco 49ers’ practice schedule began a day later than normal with a Monday night showdown against the Detroit ...

(Jose Carlos Fajardo/Bay Area News Group) MIAMI GARDENS, Fla. — Nick Bosa will suit up for the 49ers and play his first regular-season game near his hometown of Fort Lauderdale. Bosa was ...