Jack Quaid and Amber Midthunder are “dialed in,” making the romantic side of Novocaine work. As previously reported, the Paramount Pictures film Quaid stars as Nate, a regular guy — except for one thing: he can’t feel physical pain.

Quaid's leading role in Novocaine feels like a natural continuation of these genre-bent everymen. He plays Nathan Caine, a mild-mannered assistant bank manager who has congenital insensitivity to pain with anhidrosis (CIPA), a genetic disorder that impacts his nervous system to the point that he can't feel pain or temperature.