Management of chromosome shape and topology in bacteria falls to three groups of proteins: the DNA topoisomerases, the structural maintenance of chromosome proteins (SMC), and the small double-strand ...
Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during ...
Anti-topoisomerase I antibodies (ATA ... of ATA to inhibit TOP1 was tested by a in house developed REEAD assay in which the generation of closed DNA circles, by the cleavage-ligation activity of TOP1, ...