They observed that the mRNA emerging from RNAP was bound to the small ribosomal subunit (30S) particularly efficiently when ribosomal protein bS1 was present, which helps the mRNA unfold in ...

For nearly 30 years, no new class of antibiotics has ... “Lariocidin binds near the decoding center of the small ribosomal subunit and prevents tRNA from moving through properly,” explained ...

Bad habits like smoking, heavy drinking and skipping exercise can start to impact a person's health as early as their mid-30s, a new study says. In fact, those three specific vices mean poorer ...

Christine M. Slover, PharmD, Infectious Diseases Fellow, Keith A. Rodvold, PharmD and Larry H. Danziger, PharmD, Professor, Department of Pharmacy Practice ...

The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

Objective: To systematically evaluate the literature to determine whether vancomycin-induced neutropenia is dose- or duration-related and provide clinicians with feasible treatment alternatives ...

Among the most hypophosphorylated PKA substrates upon AKAP11 depletion was Ser12 of RPL34; we speculate that AKAP11 may bring the RIα- Cα in proximity to RPL34 at some point during the life cycle of ...

We also found an HTT association with nearly all subunits of the canonical Mediator complex (20/26), a major transcriptional regulator, with preferential enrichment of the MED15 subunit in the tail ...

Pink colour window behind the bar graphs shows the empirical cut-off of 0.8 correlation coefficient. (C) Interspecies correlation plot between Dip2 and various control proteins like Ribosomal 60s ...