Woolly mammoths are a step closer to roaming the world again after scientists engineered a ‘woolly mouse’. It may be on a ...

The mice are Agouti Viable Yellow, naturally occurring mutants, which, though genetically identical, have coats that vary in color—a phenomenon that researchers have long studied as an example of ...

For instance, in normal, healthy mice, the agouti genes are kept in the "off" position by the epigenome, which attaches methyl groups to the corresponding regions of DNA, resulting in the DNA's ...

Engineered mice also have lighter coat colors due to a modified version of the MC1R gene, which regulates melanin production resulting in golden hair rather than the black/agouti wild type mouse ...

The remaining male pup developed into a fertile adult male with the same agouti coat colour as the B6C3F1 tail-tip cell donor. As oocytes of B6D2F1 mice do not carry the agouti mutation ...