Both function by binding to protein receptors on cells. The four primary receptors — alpha-1, alpha-2, beta-1, and beta-2 — are located in different body areas. The impact of norepinephrine and ...

The Catalytic Fund is a not-for-profit Community Development Financial Institution that provides non-traditional financing products and related property development advisory services.

Get Instant Summarized Text (Gist) A novel drug compound has been identified that selectively activates delta opioid receptors, offering pain relief without the dangerous side effects associated ...

A new way to watch catalytic reactions happen at the molecular level in real time could lead to better fundamental understanding and planning of the important reactions used in countless ...

The anaphylatoxin C3a mediates pro-inflammatory and chemotactic functions through the G protein-coupled receptor C3aR. While the active structure of the C3a-C3aR-G i complex has been determined, the ...

Abstract Guanylate cyclase-A, the receptor for atrial natriuretic factor, contains a protein kinase–like domain and a catalytic domain in the intracellular region. To investigate the active site (the ...

The effector proteolytically targets a key receptor while its activity is counteracted by host-mediated phosphorylation, revealing a dynamic interplay that fine-tunes symbiotic interactions. The ...

Nuclear receptors form a family of proteins capable of accommodating a wide variety of small molecules in their ligand binding domain, ranging from therapeutic compounds to endocrine-disrupting ...

Current therapies fail to attenuate such complications. Here, we identify formyl-peptide receptor type 2 (FPR2) as a therapeutic target to treat heart and lung dysfunction associated with inflammatory ...

Washington State House Bill 2153, developed with the help of the King County Prosecuting Attorney’s Office, is now in effect, adding laws to deter catalytic converter theft in Washington state ...

The proposal, titled "Cell Type Specificity of Neurokinin-1 Receptor Antagonists on Cognitive Improvement," aims to understand the precise neurological mechanisms and cellular targets responsible ...