Figure 1: A side-by-side comparison of the inflammatory process in a cutaneous setting. Several advantages are evident in the work of Thepen and colleagues 1. By targeting a receptor that is ...

IDO1 and PDL1 are immune checkpoints with key roles in immune system regulation. Their relevance stems from their ability to suppress T-cell function. T-cells are vital to the body’s immune response ...

The melanocortin 1 receptor (MC1R or alpha melanocytestimulating ... that numerous MC1R gene variants predisposed individuals to cutaneous melanoma. In stratified analyses, the genetic ...

Investigators found that denileukin diftitox, which targets the interleukin-2 receptor, achieves objective response rates in 44% of patients with cutaneous T-cell lymphoma, with a median duration ...

High-titer anti-M3R antibodies are associated with more severe gastrointestinal symptoms and diffuse disease in systemic ...