DNA sequencing ... a heat-resistant enzyme that's active at unusually high temperatures: 70° to 80°C. That discovery led to the invention of the polymerase chain reaction, or PCR (as in the ...

In this article, Momin Shah discusses how to ensure that NGS protocols are optimized from the outset to save time and costs ...

They're made of extended nucleotide sequences, similar to DNA, but they can also act as enzymes to facilitate reactions ... with a particular focus on RNA polymerase ribozymes—RNA molecules ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

A new ML-guided platform can design thousands of new enzymes, predict how they will behave in the real world, and test their ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the ...

In the new study, researchers homed in on a part of the viral machinery called the viral polymerase complex ... Once the researchers worked out the structure of the enzyme, they took a closer look at ...

The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...