These mutations pinpoint antifungal drug targets ... 448877) were prepared by nitrous deamination, as described previously (Zakrzewska et al., 2005). Briefly, 10 g Chitosan was dissolved in 200 mL 10% ...

Figure 1 Typical chronology of cellular events during tumour progression. Figure 2 Formation of different reactive products from nitric oxide. Pleiotropic biological effects of NO may depend upon this ...

Gene sequencing of these D1.1 viruses has found a mutation that helps the virus copy itself more efficiently into the cells of mammals, including people. This change hasn’t been seen in other D1 ...

Feb. 7, 2025 — A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 ...

ZJU-Hangzhou Global Scientific and Technological Innovation Canter, Zhejiang University, Hangzhou, Zhejiang 311215, China College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, ...

NASA iCOOL (Center for the Integration of the Origins of Life) and School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, United States Institute of ...

Editing may lead to non-synonymous amino acid mutations, RNA secondary structure alterations, pre-mRNA processing changes, and microRNA-mRNA redirection, thereby affecting multiple cellular processes ...

Aging is an inevitable progressive decline in physiological organ function that increases the chance of disease and death. The renin–angiotensin system (RAS) is involved in the regulation of ...

2 Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China 3 State Key Laboratory of Liver Research, Li Ka Shing Faculty of Medicine, University of ...