GenAI offers a realistic path forward in tackling previously undruggable targets, with the potential to reshape the entire ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

A team at UC Davis has created a new drug called JRT that mimics LSD’s brain-healing effects without the hallucinogenic side ...

Proteins play a central role in virtually every disease. They are the building blocks of life, serving as essential ...

A team at UCSF and Gladstone Institutes developed new drug candidates that show great promise against the virus that causes ...

Another reason for choosing a particular modality is that it is a team’s specialty. Strategic choices can be less about determining which modality best fits a potential target than about choosing a ...

University of California, Davis researchers have developed a new, neuroplasticity-promoting drug closely related to LSD that ...