We hypothesized that the syntrophins function as molecular anchors to link dystrophin and utrophin to other cell structures. To understand the organization of the utrophin complex at neuromuscular ...

Background: Dystrophin is a key protein encoded by the DMD gene, serves as a scaffold linking the cytoskeleton to the extracellular matrix that plays a critical role in muscle contraction, relaxation, ...

DMD is a complex disease, Kelly said ... for which it plans to pursue accelerated approval—based on FDA feedback—with dystrophin expression as a surrogate endpoint. In September 2024, the company ...

It is caused by a mutation in the gene for the dystrophin protein, leading muscle cells to be fragile and easily damaged. Disease-related mortality is most often related to cardio-respiratory failure, ...

Far from being solo operators, most single-celled microbes are in complex relationships. In the ocean, the soil, and your gut, they might battle and eat each other, exchange DNA, compete for ...

Fans first heard the track on January 4, when Scott performed it during the College Football Playoff National Championship Halftime Show at Atlanta’s Mercedes-Benz Stadium. “Four-by-four, I ...