Given that alcohol is the most frequent functional group found in bioactive natural products and marketed drugs, and is a ...

To accelerate enzyme engineering, researchers used cell-free protein synthesis (CFPS) to generate sequence-function data, eliminating transformation and cloning steps. This enabled rapid construction ...

CCM Biosciences has developed groundbreaking compounds that activate the enzyme SIRT3, potentially reversing age-related cellular decline. These first-in-class drugs outperform existing treatments and ...

Frontiers Science Center for Transformative Molecules, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, ...

This enzyme could be transformative for industry, it not only speeds up a crucial class of chemical transformation, but does so with remarkable precision, even when working with challenging chemical ...

Get Instant Summarized Text (Gist) A novel enzyme, S N Ar1.3, has been developed to catalyze nucleophilic aromatic substitution reactions with high efficiency and selectivity under mild conditions ...

Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Educational of China), Key Laboratory of Phytochemical R&D of Hunan Province, and Key Laboratory of the ...

Temperature affects enzyme-catalysed reactions by influencing the rate at which they occur. For a reaction to occur between an enzyme and substrate the two molecules need to collide. At lower ...