By analyzing the arrangement of vertebrae in the spines of nearly 400 species of tetrapods—a group of animals with four limbs ...

Researchers at Karolinska Institutet and Uppsala University have developed a powerful new technique to better understand how ...

Gene regulation in immune cells refers to the mechanisms used by immune cells to increase or decrease the production of specific gene products. Ivashkiv and colleagues show that IL-10 inhibits the ...

United States Center for Eukaryotic Gene Regulation, Penn State University, University Park, Pennsylvania 16802, United States Department of Chemistry, The Pennsylvania State University, University ...

Reference: Guan D, Bai Z, Zhu X, et al. Genetic regulation of gene expression across multiple tissues in chickens. Nat Genet. 2025. doi: 10.1038/s41588-025-02155-9 ...

Dr Sarah Marzi Department of Brain Sciences and UK DRI Scientists are developing better ways to study gene regulation – the process through which the expression of genes is controlled by cells.

The U.S. Food and Drug Administration (FDA) has authorized Sineugene Therapeutics to begin a Phase 1/2a trial of its experimental gene therapy, SNUG01, in people with amyotrophic lateral sclerosis ...

Contributed by Jian-Kang Zhu; received November 8, 2024; accepted March 7, 2025; reviewed by Cao Xu and Ramin Yadegari ...

The modified ZFP189 activated hundreds of transposable elements, which the researchers thought might trigger a domino effect on gene regulation. When they dug deeper, they discovered that the awakened ...

This process has been an important factor in eukaryotic evolution, yet the number and timing of these events remains unresolved. One of the main results of secondary endosymbiosis has been the ...

Dvorak et al. discussed the effect of intron position on gene expression regulation in their Brief research report article. Longer first introns were found to be a general property of eukaryotic gene ...