Altogether, these examples demonstrate how autophagy can prevent apoptosis and show the metabolic pathways through which cytoprotective autophagy can be stimulated. Autophagy-mediated cellular ...

the majority of studies have focused on the role of apoptosis in cell death. Emerging evidence suggests that additional cell-death pathways are crucial for the triggering of inflammation and immunity.

Increasing evidence suggests that PCD plays a crucial role in CIO. In this review, we explore recent findings on the role of PCD pathways in CIO, particularly in the context of apoptosis, autophagy, ...

Deregulated apoptosis may also be the leading cause of cancer therapy ... 11 and -12), which allow for interactions with other proteins, and link with signalling pathways. In another study, the ...

Consecration and 10 steps to cleansing. They do dovetail with our responsibilities. What is required of a priest and how does the priesthood parallel with those who are Christians? Can you draw a ...

The thymus plays a pivotal role in generating a highly-diverse repertoire of T lymphocytes while preventing autoimmunity. Thymus seeding progenitors (TSPs) are a heterogeneous group of multipotent ...

One of the issues when unravelling the genetic cause of a complex disease is the difficulty in uncoupling the primary and secondary defects, which may result in inadvertently focusing on a wrong ...

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...