Injury of podocytes, if recognized at all ... TGF-β1 causes an increase in mesangial matrix deposition and glomerular basement membrane (GBM) thickening and may promote podocyte apoptosis ...

because immortalized glomerular human endothelial cells did not respond to insulin. In podocytes, as in muscle and adipocytes, GLUT4 translocation is dependent on an intact actin cytoskeleton to ...

Walden’s programs address novel targets for therapeutic intervention, directly targeting two cell types critical for kidney function: podocytes and proximal tubular cells. Dysfunction of these ...

As shown in Figure 3A, the number of global publications on the endoplasmic reticulum of glomerular podocytes has shown an upward trend in the past 19 years, with the number of publications increasing ...

Basement membranes (BMs) are complex macromolecular networks underlying all continuous layers of cells. Essential components include collagen IV and laminins, which are affected by human genetic ...

Podocytes are specialized epithelial cells that cover the outer surfaces of glomerular capillaries. Unique cell junctions, known as slit diaphragms, which feature nephrin and Neph family proteins in ...