Neurons in the brains of mice tell them to stop eating when they’ve had enough food – and since people probably have the same ...

However, in people with diabetes, the pancreas does not secrete insulin, or the cells are not sensitive to its effects. The pancreas releases glucagon hormone into the bloodstream to raise blood ...

Traditionally, blood sugar regulation has been attributed to the hormones insulin and glucagon, both produced by the pancreas. Insulin lowers blood glucose by promoting its uptake into cells ...

During fasting or exercise, immune cells (red) migrate to the pancreas and stimulate glucagon-producing cells (orange) to regulate blood sugar, with cell nuclei shown in blue. “For decades ...

Recent research has highlighted the importance of glucagon-like peptide-1 (GLP-1) and its analogs in this context, as they play a significant role in beta-cell function and survival. Various ...

Objective—Glucagon-like peptide 1 (GLP-1) exerts beneficial antidiabetic actions via effects on pancreatic β- and α-cells. Previous studies have focused on the improvements in β-cell function ...

The absolute risk for thyroid cancer is low among patients receiving glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy, but risk is elevated in the first year of treatment, according to a ...

Endometrial cancer (EC) ranks as the second most prevalent gynecologic malignancy globally, with approximately 189,000 new ...

Xeris Pharmaceuticals has teamed up with the American Diabetes Association (ADA) to raise awareness of the importance of prescribing glucagon, positioning the partners to address a fundamental ...

We found IL-8 expression in human islets to be localized to glucagon-positive endocrine cells, suggesting that islet IL-8 is mainly α-cell derived (Fig. 7A, 1-15). Indeed, by electron microscopy ...

a premier provider of cell-based assay solutions, has introduced its new Glucagon Receptor (GCGR) Reporter Assay to accompany its already popular Glucagon-like Peptide-1 Receptor (GLP-1R ...