Successful test in breast cancer patients: the active agent digoxin, a cardiac medication, dissolves clusters of circulating breast cancer cells in the blood, thus reducing the risk of metastases ...

Some tumor types spread throughout the body and develop metastases instead of staying at their original location.

Hence, researchers often simulate the brain as a network of coupled neural masses, each described by a mean-field model. These models capture the essential features of neuronal populations while ...

Ion channels are integral membrane protein assemblies that modulate the flow of ions into and out of a cell or organelle, leading to generation of electrical signals. Opening (gating) of ion ...

In a new study, a team led by medical researchers at The Ohio State University has determined that these vesicles contain an ion channel—a protein that opens a corridor allowing electrical ...

Study uncovers a pathogenic subset of memory T-cells that promote tissue inflammation and highlights a potential target for treating nasal polyps and other inflammatory airway diseases. Study ...

In two patients, however (B.C. and N.G.), the additional observation of low arterial-blood pH confirmed significant renal retention of hydrogen ion. Table 3 Acid Excretion in Patients with ...

A combination of the ion channel inhibitors Lomerizine (Lom), YM872 and oxATP, to inhibit voltage-gated Ca 2+ channels, Ca 2+ permeable AMPA receptors, and purinergic P2X 7 receptors respectively, ...

By utilizing the Flou-3-AM dye to bind to free intracellular calcium ions and measuring the resulting fluorescence intensity through flow cytometry, changes in platelet intracellular calcium ion ...