Fig 3. Relationship between MAP2K1 class, clinical features, and survival. (A) PFS and (B) OS in class 2 versus other MAP2K1 mutant tumors in the whole MAPK targeted therapy-treated cohort. (C) PFS ...

Correlates of Cetuximab Efficacy in Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma Previously Treated With Immunotherapy MAP2K1/MEK1 mutations are potentially actionable drivers in ...

Langerhans cell histiocytosis (LCH) is a disease caused by clonal expansion of CD1a+/CD207+ cells and is characterized by organ involvement and dysfunction. Treatment of LCH in children is ...

Follicular lymphoma (FL) is a mature lymphoid malignancy derived from germinal center B cells, accounting for approximately 22% of all non-Hodgkin's lymphomas. It is common in middle-aged and older ...

The web service implements a very simple REST-style API. This package makes requests by the HTTP protocol to retrieve the data. Hence, fast Internet access is required for a proper use of OmnipathR.

Angiogenesis requires the temporal coordination of the proliferation and the migration of endothelial cells. Here, we investigated the regulatory role of microRNAs (miRNAs) in harmonizing angiogenesis ...