Fig 3. Relationship between MAP2K1 class, clinical features, and survival. (A) PFS and (B) OS in class 2 versus other MAP2K1 mutant tumors in the whole MAPK targeted therapy-treated cohort. (C) PFS ...

Correlates of Cetuximab Efficacy in Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma Previously Treated With Immunotherapy MAP2K1/MEK1 mutations are potentially actionable drivers in ...

Langerhans cell histiocytosis (LCH) is a disease caused by clonal expansion of CD1a+/CD207+ cells and is characterized by organ involvement and dysfunction. Treatment of LCH in children is ...