Many mitochondrial diseases have been difficult to study and treat due to the inherent challenges in accessing mitochondrial DNA (mtDNA). Now, researchers have optimized mitochondrial-targeted ...

Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new ...

Laboratory of Advanced Optoelectronic Materials, Suzhou Key Laboratory of Novel Semiconductor-Optoelectronics Materials and Devices, State and Local Joint Engineering Laboratory for Novel Functional ...

Previous work led by Khan had discovered that in patients with ERneg breast cancer, epithelial cells from unaffected, healthy breast tissue in the breast opposite of the cancerous breast had ...

The method, called 'Perturb-multiome,' uses CRISPR to knock out the function of individual transcription factors across many blood cells at once. The researchers then perform single-cell analyses ...

A novel genomic screening tool, "Perturb-multiome," utilizes CRISPR to knock out transcription factors in blood cells, allowing single-cell analyses to determine gene activation and accessibility.

Meta-analyses and validation studies using metabolomics data are increasingly performed, as exemplified in the growing field of metabolomics epidemiology. (1) Due to the broad chemical diversity of ...

Tissue engineering strategies predominantly rely on the production of living substitutes, whereby implanted cells actively participate in the regenerative process. Beyond cost and delayed graft ...