The nicotinic acetylcholine receptors (nAChRs) are the most well understood membrane receptors for neurotransmitters at the structural and functional level. They are integral allosteric membrane ...

Most studies have focused on forms of LTD that are triggered by synaptic activation of either NMDARs (N-methyl-D-aspartate receptors) or metabotropic glutamate receptors (mGluRs). Converging ...

Most mammals maintain their body temperature around 37°C, whereas in hibernators it can approach 0°C without triggering a thermogenic response. The remarkable plasticity of the thermoregulatory system ...

All LTD experiments were done in presence of 50 μM picrotoxin and 5 μM L689560 (trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline, a very potent antagonist of the ...

Instead, a single odorant will bind to multiple types of odorant receptors, and thus, each olfactory receptor neuron may respond to multiple odorants. So how does the brain encode mixtures of odorants ...

Additionally, it has been discovered that astrocytes express large amounts of neurotransmitter receptors and transporters (Wang and Bordey, 2008). Since a neuron’s pre- and ... (A) Functional block ...