ahajournals.org1d
Fast Degradation of MecciRNAs by SUPV3L1/ELAC2 Provides a Novel Opportunity to Tackle Heart Failure With Exogenous MecciRNA
BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.
Frontiers19d
Nicotinamide Riboside and Metformin Ameliorate Mitophagy Defect in Induced Pluripotent Stem Cell-Derived Astrocytes With POLG Mutations
Graphical Abstract. Hypothetical mechanisms of mitophagy dysfunction in POLG-mutant astrocytes. Nicotinamide riboside was provided by Evandro Fei Fang (University of Oslo, Norway). The cells were ...
C&EN20d
Harnessing an MMP-Independent NIR Probe Unveiling the Different Mitochondrial Cristae Changes during Mitophagy and Ferroptosis under STED Microscopy
State Key Laboratory of Crystal Materials, Department of Otolaryngology-Head and Neck Surgery, Shandong Institute of Otorhinolaryngology, Shandong Provincial ENT Hospital, Shandong University, Jinan, ...
ahajournals.org22d
Abstract TP6: Thymosin alpha 1 promotes neuron survival by enhancing mitophagy after AIS
Background: Thymosin alpha 1 (Tα1) had been used in kinds of inflammatory and immunodeficiency diseases as an immunomodulator. According to our clinic observation, patients with acute ischemic stroke ...
Frontiers24d
Secretory mitophagy: an extracellular vesicle-mediated adaptive mechanism for cancer cell survival under oxidative stress
1 Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, United States 2 Laboratory of Molecular Virology, School of Systems Biology, George Mason University, ...
ABC News25d
Heart disease remains leading cause of death in US, new report finds
In 2022, more than 941,600 Americans died from cardiovascular disease. Heart disease remains the leading cause of death in the United States, according to a new report. The American Heart ...
Medical Xpress29d
Drug shows promise in preventing heart failure post-heart attack in mice
Healthy mitochondria are critical drivers of the processes that protect and repair the heart and other muscles. PR-364 altered the mitochondria in several beneficial ways: By increasing mitophagy ...
C&EN29d
The P2X7-Mediated Mitochondrial ROS as an Emerging Core Target of Tuftsin Nanoparticles in Severe Acute Pancreatitis Therapy via Regulating Mitophagy
Department of Critical Care Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, People’s Republic of China ...